Rheumatoid arthritis (RA) is a widely prevalent (1–3%) chronic systemic disease thought to have an autoimmune component1; both humoral1–4 and cellular5,6 mechanisms have been implicated. Primary osteo...
In a rheumatoid joint, a hierarchical network of cytokines controls immunological processes that promote autoimmunity, chronic inflammation and tissue destruction in rheumatoid arthritis. As proposed ...
Rheumatoid arthritis is a prototypical autoimmune disease that causes joint inflammation and destruction1. There is currently no cure for rheumatoid arthritis, and the effectiveness of treatments vari...
Higher prevalence of autism in offspring born to mothers with rheumatoid arthritis has been reported in observational studies. We investigated (a) the associations between maternal and offspring’s own...
Soumya Raychaudhuri, Paul de Bakker and colleagues report fine mapping of the rheumatoid arthritis associations within the MHC by combining genome-wide SNP data and imputation of classical HLA alleles...
The first biomarker associated with the rheumatoid arthritis is rheumatoid factor (RF) and since the earliest reports a role has been proposed in the diagnosis and in the prediction of clinical featur...
Sarcopenia, a disorder that involves the generalized loss of skeletal muscle strength and mass, was formally recognized as a disease by its inclusion in the International Classification of Diseases in...
Rheumatoid arthritis is a prototypical autoimmune disease that causes joint inflammation and destruction1. There is currently no cure for rheumatoid arthritis, and the effectiveness of treatments vari...
Rheumatoid arthritis usually begins in one joint but spreads to other joints as the disease progresses. Elena Neumann and her colleagues show that rheumatoid arthritis synovial fibroblasts (RASFs) may...
The amount of clinical, serological and experimental evidence linking periodontitis to rheumatoid arthritis is constantly increasing. In this Review, Potempa and colleagues lay out the case for period...
Rheumatoid arthritis is a prototypical autoimmune disease that causes joint inflammation and destruction1. There is currently no cure for rheumatoid arthritis, and the effectiveness of treatments vari...
Although both rheumatoid factor (RF) and anticyclic citrullinated peptide antibodies (anti-CCP) are useful for diagnosing rheumatoid arthritis (RA), the im
The present study was designed to investigate the relationship of rheumatoid factor positivity to the prevalence of joint manifestations in type 2 diabetes which are not attributable to rheumatoid art...
The amount of clinical, serological and experimental evidence linking periodontitis to rheumatoid arthritis is constantly increasing. In this Review, Potempa and colleagues lay out the case for period...
Learn about rheumatoid arthritis including Information on the signs, syptoms and treatment of Rheumatoid Arthritis from the Johns Hopkins Arthritis Center.
Inherited susceptibility to rheumatoid arthritis (RA) is associated with the DRB1 genes encoding the human leukocyte antigen (HLA)-DR4 and HLA-DR1 molecule
Here, John Isaacs describes the societal implications of rheumatoid arthritis and how diagnosis and treatment approaches have evolved. He also discusses the future approaches needed for the complete m...
What is rheumatoid arthritis? Who's at risk for juvenile RA? Get the facts on causes of rheumatoid arthritis, prevention, and the in-depth RA information you need.
Rheumatoid arthritis-associated interstitial lung disease (RA-ILD) is a major contributor to rheumatoid arthritis (RA) related morbidity and mortality. Ear
The authors identify in patients with rheumatoid arthritis a pathogenic subset of CD4+ T cells that augments B cell responses within inflamed tissues. Michael Brenner and colleagues identify a subset ...
