Using vaginally applied estrogen to ease menopause symptoms likely doesn't increase a woman's risk of heart disease or certain cancers, a U.S. study suggests. Many women have been reluctant to use hor...
Estrogen receptor alpha (ER)-positive breast cancer is commonly treated with endocrine therapies, including antiestrogens that bind and inhibit ER activity, and aromatase inhibitors that suppress estr...
Estrogen receptor alpha (ER)-positive breast cancer is commonly treated with endocrine therapies, including antiestrogens that bind and inhibit ER activity, and aromatase inhibitors that suppress estr...
Through intracellular receptors, estrogens control growth, differentiation and function of not only reproductive tissues, but also other systems1,2,3. Estrogen receptors are ligand-dependent transcrip...
Watch CBS News Updated on: July 2, 2025 / 8:59 PM EDT/ CBS News Women using a certain type ofhormone therapyto treat menopause symptoms could be at higher risk forbreast cancer, according to a new st...
Estrogens regulate physiological and pathological processes in both women and men. Traditionally, the actions of 17β-estradiol, the predominant and most potent endogenous estrogen, were ascribed to tw...
Plus, all the expert tips and tricks for preventing the "luteal phase uglies." We may earn commission from links on this page, but we only recommend products we love. Promise. For about two weeks of e...
Estrogen is reported to be involved in thrombopoiesis and the disruption of its signaling may cause myeloproliferative disease, yet the underlying mechanisms remain largely unknown. GATA-binding facto...
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Development of breast cancer involves genetic factors as well as lifetime exposure to estrogen. The precise molecular mechanisms whereby estrogens influence breast tumor formation are poorly understoo...
The estrogen signaling pathway has been reported to modulate prostate cancer (PCa) progression through the activity of estrogen receptors α and β (ERα and ERβ). Given that selective estrogen receptor ...
The present study evaluated the possible antidepressant-like action of the natural estrogen 17β-estradiol (E2, 2.5–10 μg/rat), the synthetic steroidal estrogen ethinyl-estradiol (EE2, 1.25–10.0 μg/rat...
Plus, all the expert tips and tricks for preventing the "luteal phase uglies." We may earn commission from links on this page, but we only recommend products we love. Promise. For about two weeks of e...
Hormonal influences such as androgens and estrogens are known contributors in the development and progression of prostate cancer (CaP). While much of the research to the hormonal nature of CaP has foc...
Proteins, covalently modified by catechol estrogens (CEs), were identified recently from the blood serum of diabetic patients and referred to as estrogenized proteins. Estrogenization of circulating i...
Estrogens are the key hormones regulating the development and function of reproductive organs in all vertebrates. Recent evidence indicates that estrogens play important roles in the immune system, ca...
An increased breast cancer risk during adulthood has been linked to estrogen exposure during fetal life. However, the impossibility of removing estrogens from the feto-maternal unit has hindered the t...
Catechol estrogens may mediate estrogen-induced carcinogenesis because 4-hydroxyestradiol induces DNA damage and renal tumors in hamsters, and this metabolite is formed in the kidney and estrogen targ...
Estrogens play important roles in uterine growth and homeostasis through estrogen receptors (ESR1 and ESR2). To address the role of ESR1-mediated tissue events in the murine uterus, we analyzed mice w...
