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Kaposi sarcoma herpesvirus–induced cellular reprogramming contrib...
The biology of Kaposi sarcoma is poorly understood because the dominant cell type in Kaposi sarcoma lesions is not known1,2,3,4. We show by gene expression microarrays that neoplastic cells of Kaposi ...
A spatially and temporally restricted mouse model of soft tissue ...
Soft tissue sarcomas are mesenchymal tumors that are fatal in approximately one-third of patients. To explore mechanisms of sarcoma pathogenesis, we have generated a mouse model of soft tissue sarcoma...
Pitfalls in diagnosis of soft tissue tumors of childhood | PPTX
The document discusses several potential pitfalls in the diagnosis of soft tissue tumors in children. It covers:
1) Misclassification of specific sarcomas like rhabdomyosarcoma subtypes and non-rhabd...
Targeting other abnormal signaling pathways in sarcoma: EGFR in s...
'Targeting other abnormal signaling pathways in sarcoma: EGFR in synovial sarcomas, PPAR-γ in liposarcomas' published in 'Targeting Treatment of Soft Tissue Sarcomas'
Characterization of Murine Sarcoma Virus (kirsten) Transformation...
SUMMARY
Kirsten sarcoma virus induces foci of morphologically altered cells in rat, mouse, and human cells in tissue culture. The kirsten sarcoma virus stock contains two viruses; one forming foci and...
Kaposi's sarcoma and its associated herpesvirus | Nature Reviews ...
Kaposi's sarcoma (KS) is the most common cancer in HIV-infected untreated individuals. Kaposi's sarcoma-associated herpesvirus (KSHV) is the infectious cause of KS. This Review discusses the insights ...
Sarcoma - Mussa Mensa | PPT
This document provides an overview of sarcomas, including:
- Sarcomas are rare tumors accounting for less than 1% of cancers. They arise from embryonic mesoderm tissue.
- The document discusses the ep...
Rob Ford died suffering from pleomorphic liposarcoma | CBC News
Former Toronto Mayor Rob Ford died Tuesday while suffering from a rare type of cancer known as pleomorphic liposarcoma. Ford endured nine rounds of chemotherapy, his chief of staff Dan Jacobs said, as...
Rob Ford died suffering from pleomorphic liposarcoma | CBC News
Former Toronto Mayor Rob Ford died Tuesday while suffering from a rare type of cancer known as pleomorphic liposarcoma. Ford endured nine rounds of chemotherapy, his chief of staff Dan Jacobs said, as...
Soft tissue sarcoma | PPTX
This document provides information on the management of soft tissue sarcoma. It discusses the clinical presentation, patterns of spread, imaging, histology, grading, staging, prognostic factors and ma...
Rob Ford died suffering from pleomorphic liposarcoma | CBC News
Former Toronto Mayor Rob Ford died Tuesday while suffering from a rare type of cancer known as pleomorphic liposarcoma. Ford endured nine rounds of chemotherapy, his chief of staff Dan Jacobs said, as...
Proteomic characterization identifies clinically relevant subgrou...
Soft tissue sarcoma is a broad family of mesenchymal malignancies exhibiting remarkable histological diversity. We portray the proteomic landscape of 272 soft tissue sarcomas representing 12 major sub...
Gemcitabine plus selinexor in selective advanced sarcomas: a phas...
Exportin-1 (XPO-1) is related to drug resistance and poor prognosis in solid tumors. Selinexor, an XPO-1 inhibitor, has shown preclinical and clinical activity in sarcomas. This Phase I study explores...
Relapsed Synovial Sarcoma: Treatment Options | Current Treatment ...
Synovial sarcoma (SS) is a fusion-driven subtype of sarcoma that is a more chemo-sensitive subtype of soft tissue sarcoma. While chemotherapy options are c
Subtype-specific genomic alterations define new targets for soft-...
Samuel Singer and colleagues report an integrative genomic analysis of soft-tissue sarcomas. They survey sequence, copy number and mRNA expression in 207 individuals diagnosed with one of seven major ...
Molecular and epigenetic oncogenesis in synovial sarcoma: implica...
The SS18::SSX oncogene is the driver of synovial sarcoma, an aggressive cancer presenting in young adults that has poor long-term outcomes. Over the past five years, significant progress has been made...
The fibroblast epigenome underlies SS18::SSX-mediated transformat...
Synovial sarcoma (SyS) is an aggressive soft-tissue malignancy that is characterised by a pathognomonic t(X;18)(p11.2;q11.2) translocation, which produces the fusion oncogene named SS18::SSX. Despite ...
Soft Tissue Sarcomas and Bone Tumors | Springer Nature Link
Sarcomas are a group of diverse, rare tumors originating in the bone and connective tissue. They comprise approximately 1% of adult malignancies and 12% of pediatric malignancies. Eighty percent of sa...
Survival Benefit of the Surgical Management of Retroperitoneal Sa...
Guidelines recommend that retroperitoneal sarcoma (RPS) be managed in a reference sarcoma center (RSC), but the benefit remains to be demonstrated. This st
Survival Benefit of the Surgical Management of Retroperitoneal Sa...
Guidelines recommend that retroperitoneal sarcoma (RPS) be managed in a reference sarcoma center (RSC), but the benefit remains to be demonstrated. This st