Dmrt1 - Moozonian

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Moo-Ai is thinking... Processing hyper-cognitive insights for 'Dmrt1'

https://doi.org/10.1038/srep42213

Genome editing reveals dmrt1 as an essential male sex-determining...

Chinese tongue sole is a marine fish with ZW sex determination. Genome sequencing suggested that the Z-linked dmrt1 is a putative male determination gene, but direct genetic evidence is still lacking....

https://doi.org/10.1038%2Fsrep42213

Genome editing reveals dmrt1 as an essential male sex-determining...

Chinese tongue sole is a marine fish with ZW sex determination. Genome sequencing suggested that the Z-linked dmrt1 is a putative male determination gene, but direct genetic evidence is still lacking....

https://doi.org/10.1038%2Fs41556-023-01224-7

DMRT1 regulates human germline commitment | Nature Cell Biology

Germline commitment following primordial germ cell (PGC) specification during early human development establishes an epigenetic programme and competence for gametogenesis. Here we follow the progressi...

https://www.academia.edu/117208090/Multiple_alternative_splicing_of_Dmrt1_during_gonadogenesis_in_Indian_mugger_a_species_exhibiting_temperature_dependent_sex_determination

(PDF) Multiple alternative splicing of Dmrt1 during gonadogenesis...

Dmrt1 is an evolutionarily conserved gene having important role in the sex determination from lower vertebrates to mammals. Recent studies show transcriptional diversity for this important gene during...

https://doi.org/10.1038%2Fnature10239

DMRT1 prevents female reprogramming in the postnatal mammalian te...

The presence or absence of the Y-chromosome gene Sry determines whether precursor cells differentiate into testicular Sertoli cells or ovarian granulosa cells in the mammalian fetus. Loss of the trans...

https://www.nature.com/articles/s41467-024-49025-2?fromPaywallRec=false

A candidate sex determination locus in amphibians which evolved b...

Most vertebrates develop distinct females and males, where sex is determined by repeatedly evolved environmental or genetic triggers. Undifferentiated sex chromosomes and large genomes have caused maj...

https://www.ncbi.nlm.nih.gov/nuccore/NM_021951

Homo sapiens doublesex and mab-3 related transcription factor 1 (...

https://link.springer.com/10.1038/s41467-024-49025-2?fromPaywallRec=true

A candidate sex determination locus in amphibians which evolved b...

Most vertebrates develop distinct females and males, where sex is determined by repeatedly evolved environmental or genetic triggers. Undifferentiated sex chromosomes and large genomes have caused maj...

https://www.nature.com/articles/s41467-021-25249-4?fromPaywallRec=true

DMRT1-mediated reprogramming drives development of cancer resembl...

In vivo reprogramming provokes a wide range of cell fate conversion. Here, we discover that in vivo induction of higher levels of OSKM in mouse somatic cells leads to increased expression of primordia...

https://link.springer.com/doi/10.1186/1477-7827-5-20

Testicular involution prior to sex change in gilthead seabream is...

Leukocytes are found within the testis of most, if not all, mammals and are involved in immunological surveillance, physiological regulation and tissue rem

https://link.springer.com/10.1186/s13039-018-0379-z?fromPaywallRec=true

Loss of DMRT1 gene in a Mos 45,XY,-9[8]/46,XY,r(9)[29]/47,XY,+idi...

A 46,XY sex reversal syndrome is characterized by discordant genetic and phenotypic sex, leading to normal external female genitalia, undeveloped gonads an